Jayne is used both as a surname and as a given name.
Surname
Billy Jayne, American television and film actor
Caroline Furness Jayne (1873–1909), American ethnologist
Erika Jayne, American dance/club music performer
Francis Jayne (1845–1921), British bishop and academic
Horace Jayne (1859–1913), American biologist, zoologist, professor at the University of Pennsylvania and author Ira W. Jayne (1882–1961), American judge Jennifer Jayne (1931–2006), English film and television actress Joey Jayne, Democratic Party member of the Montana House of Representatives Joseph Lee Jayne (1863–1928), rear admiral in the United States Navy, veteran of the Spanish–American War and World War I Keith Jayne (born 1960), a British television actor Mark Jayne, American wrestler Mitchell F. Jayne (1928–2010), emcee and upright bass player in The Dillards bluegrass band Randy Jayne (born 1944), Managing Partner at Heidrick & Struggles Robert Jayne (born 1973), American actor Roland Everett Jayne (1886–1937), Methodist clergyman and biographer Richard Jayne (1930-2022), Historian and prisoner of war Sam Jayne, vocalist/guitarist of indie band Love as Laughter, formerly of Lync. Silas Carter Jayne (1907–1987), implicated in the 1955 murder of three young boys in Chicago William Jayne (1826–1916), Abraham Lincoln’s personal physician, first Governor of the Dakota Territory, Delegate to the House of Representatives, three terms as mayor of Springfield, Il, from 1876