In 1796, Daniel Morgan Boone, his oldest son, traveled with other adventurers in boats to St. Charles County, in eastern Missouri, where they took lands under certificates of cession from Charles Dehault Delassus, the Spanish lieutenant-governor of Upper Louisiana, resident at St. Louis. There were four families, all settling upon Femme Osage Creek, six miles above its junction with the Missouri, some twenty-five miles above the town of St. Charles, and forty-five by water from St. Louis.
Thither they were followed, apparently in the spring of 1799, by Daniel Boone and wife and their younger children. The departure of the great hunter, now in his sixty-fifth year, was the occasion for a general gathering of Kanawha pioneers at the home near Charleston. They came on foot, by horseback, and in canoe, from far and near, and bade him a farewell as solemnly affectionate as though he were departing for another world; indeed, Missouri then seemed almost as far away to the West Virginians as the Klondike is to dwellers in the Mississippi basin to-day--a long journey by packhorse or by flatboat into foreign wilds, beyond the great waterway concerning which the imaginations of untraveled men often ran riot.
The hegira of the Boones, from the junction of the Elk and the Kanawha, was accomplished by boats, into which were crowded such of their scant herd of live stock as could be accommodated. Upon the way they stopped at Kentucky towns along the Ohio, either to visit friends or to obtain provisions, and attracted marked attention, for throughout the West Boone was, of course, one of the best-known men of his day. In Cincinnati he was asked why, at his time of life, he left the comforts of an established home again to subject himself to the privations of the frontier. "Too crowded!" he replied with feeling. "I want more elbow-room!"
Arriving at the little Kentucky colony on Femme Osage Creek, where the Spanish authorities had granted him a thousand arpents[17] of land abutting his son's estate upon the north, he settled down in a little log cabin erected largely by his own hands, for the fourth and last time as a pioneer. He was never again in the Kanawha Valley, and but twice in Kentucky--once to testify as to some old survey-marks made by him, and again to pay the debts which he had left when removing to Point Pleasant.