Ceduovirus (synonyms c2-like viruses, c2-like phages, C2likevirus) is a genus of viruses in the family Siphoviridae, unassigned to a sub-family. Bacteria serve as the natural host, with transmission achieved through passive diffusion. There are 34 species in this genus.
Taxonomy
The following species are recognized:
Lactococcus virus 05802
Lactococcus virus 20R03M
Lactococcus virus 37203
Lactococcus virus 50102
Lactococcus virus 50504
Lactococcus virus 5171F
Lactococcus virus 62402
Lactococcus virus 62403
Lactococcus virus 62606
Lactococcus virus bIBB14
Lactococcus virus bIBBA3
Lactococcus virus bIBBAm4
Lactococcus virus bIBBE1
Lactococcus virus bIBBL12
Lactococcus virus bIBBp6-4
Lactococcus virus bIL67
Lactococcus virus blBB94p4
Lactococcus virus c2
Lactococcus virus CHPC116
Lactococcus virus CHPC122
Lactococcus virus CHPC966
Lactococcus virus CHPC967
Lactococcus virus CHPC972
Lactococcus virus CHPC1020
Lactococcus virus CHPC1170
Lactococcus virus CHPC1182
Lactococcus virus CHPC1183
Lactococcus virus CHPC1242
Lactococcus virus D4410
Lactococcus virus D4412
Lactococcus virus LacS15
Lactococcus virus M5938
Lactococcus virus PCB1
Lactococcus virus PCS1
Structure
Ceduoviruses are nonenveloped, with a head and tail. The prolate head is about 56 nm long and 41 nm wide and has a collar. The tail is cross-banded, is about 86-111 nm long, 8 nm wide, and has short tail fibers. Genomes are linear, around 22kb in length.
Genome
Some species have been fully sequenced. They range between 22k and 23k nucleotides, with 37 to 39 proteins. Complete genomes are available here
Life cycle
Viral replication is cytoplasmic. The virus attaches to the host cell's adhesion receptors using its terminal fibers, and viral exolysin degrades the cell wall enough to eject the viral DNA into the host cytoplasm via long flexible tail ejection system. Replication follows the DNA strand displacement, via replicative transposition model. DNA templated transcription is the method of transcription. Bacteria serve as the natural host. Transmission routes are passive diffusion.
History
According to ICTV's 1996 report, the genus C2likevirus was first accepted under the name c2-like phages, assigned only to family Siphoviridae. The whole family was moved to the newly created order Caudovirales in 1998, and the genus was renamed to c2-like viruses in ICTV's seventh report in 1999. In 2012, the genus was renamed again, this time to C2likevirus. The genus was later renamed to Ceduovirus.