The 2021 Challenger La Manche was a professional tennis tournament played on indoor hard courts. It was the 28th edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Cherbourg, France between 8 and 14 February 2021.
Singles main-draw entrants
Seeds
1 Rankings are as of 1 February 2021.
Other entrants
The following players received wildcards into the singles main draw: Kenny de Schepper Evan Furness Matteo Martineau
The following players received entry into the singles main draw as alternates: Lukáš Klein Alex Molčan Nino Serdarušić
The following players received entry from the qualifying draw: Titouan Droguet Jonáš Forejtek Michael Geerts Nathaniel Lammons
The following player received entry as a lucky loser: Corentin Denolly
Champions
Singles
Ruben Bemelmans def. Lukáš Rosol 6–4, 6–4.
Doubles
Lukáš Klein / Alex Molčan def. Antoine Hoang / Albano Olivetti 1–6, 7–5, [10–6].