The 2012 American Express – TED Open was a professional tennis tournament played on hard courts. It was the 25th edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Istanbul, Turkey between 10 and 16 September 2012.
Singles main-draw entrants
Seeds
1 Rankings are as of August 27, 2012.
Other entrants
The following players received wildcards into the singles main draw: Haluk Akkoyun Durukan Durmus Baris Erguden Efe Yurtacan
The following players received entry from the qualifying draw: Maximilian Abel Lewis Burton Riccardo Ghedin James McGee
Champions
Singles
Dmitry Tursunov def. Adrian Mannarino, 6–4, 7–6(7–5)