Handley is a surname. Notable people with the surname include:
Brian Handley, soccer player
Benjamin Handley (1784–1858), English politician and member of parliament for Boston Carol Handley, Classics educator Chris S. Handley, comic collector in United States v. Handley David Handley (farmer), activist Dick Handley (1922—2012), American football player Elizabeth Handley-Seymour (c. 1873–1948), English fashion designer Eric Handley CBE (1926–2013), professor of Greek at Cambridge and University College, London George Handley (disambiguation), multiple people, including George Handley (politician) (1752–1793), American politician, Governor of Georgia, 1788–1789: George Handley (footballer, born 1868) (1868–1938), English footballer George Handley (footballer, born 1886) (1886–1952), English footballer George Handley (footballer, born 1912) (1912–1943), English footballer George B. Handley, professor of humanities at Brigham Young University Harold W. Handley, Indiana governor Jody Handley, English footballer Joe Handley, premier of Northwest Territories, Canada Lee Handley (1913–1970), Major League baseball player Paul M. Handley, American journalist, wrote The King Never Smiles (biography of Thai King Bhumibol) Ray Handley, American football coach Taylor Handley, actor Tommy Handley, comedian Vernon Handley, conductor Wayne Handley, airshow performer Wal Handley, motorcycle racer