Antipater (; ; c. 400 BC319 BC) was a Macedonian general and statesman under the successive kingships of Philip II of Macedon and his son, Alexander the Great. In the wake of the collapse of the Argead house, his son Cassander would eventually come to rule Macedonia as a king in his own right.

In 320 BC, Antipater was elected regent of all of Alexander the Great's Empire but died the following year. In a perplexing turn of events, he chose an infantry officer named Polyperchon as his successor instead of his son Cassander, and a two-year-long power struggle (the Second War of the Diadochi) ensued.

Antipater

Career under Philip and Alexander

Nothing is known of his early career until 342 BC, when he was appointed by Philip to govern Macedon as his regent while the former left for three years of hard and successful campaigning against Thracian and Scythian tribes, which extended Macedonian rule as far as the Hellespont. In 342 BC, when the Athenians tried to assume control of the Euboean towns and expel the pro-Macedonian rulers, he sent Macedonian troops to stop them. In the autumn of the same year, Antipater went to Delphi, as Philip's representative in the Amphictyonic League, a religious organization to which Macedon had been admitted in 346 BC.

Antipater

After the triumphal Macedonian victory at the Battle of Chaeronea in 338 BC, Antipater was sent as ambassador to Athens (337–336 BC) to negotiate a peace treaty and return the bones of the Athenians who had fallen in the battle.

Antipater

He started as a great friend to both the young Alexander and the boy's mother, Olympias, and aided Alexander in the struggle to secure his succession after Philip's death, in 336 BC.

He joined Parmenion in advising Alexander the Great not to set out on his Asiatic expedition until he had provided by marriage for the succession to the throne. On the king's departure in 334 BC, he was left regent in Macedonia and made "general (strategos) of Europe", positions he held until 323 BC. The European front was to prove initially quite agitated, and Antipater also had to send reinforcements to the king, as he did while the king was at Gordium in the winter of 334–333 BC.

The Persian fleet under Memnon of Rhodes and Pharnabazus was apparently a considerable danger for Antipater, bringing war in the Aegean sea and threatening war in Europe. Luckily for the regent, Memnon died during the siege of Mytilene on the isle of Lesbos and the remaining fleet dispersed in 333 BC, after Alexander's victory at the Battle of Issus.

More dangerous enemies were nearer home; tribes in Thrace rebelled in 332 BC, led by Memnon of Thrace, the Macedonian governor of the region, followed shortly by the revolt of Agis III, king of Sparta.

The Spartans, who were not members of the League of Corinth and had not participated in Alexander's expedition, saw in the Asian campaign the long-awaited chance to take back control over the Peloponnese after the disastrous defeats at the Battle of Leuctra and Battle of Mantinea. The Persians generously funded Sparta's ambitions, making possible the formation of an army 20,000 strong. After assuming virtual control of Crete, Agis tried to build an anti-Macedonian front. While Athens remained neutral, the Achaeans, Arcadians and Elis became his allies, with the important exception of Megalopolis, the staunchly anti-Spartan capital of Arcadia. In 331 BC Agis started to besiege the city with his entire army, forcing Antipater to act.

So as not to have two enemies simultaneously, Antipater pardoned Memnon and even let him keep his office in Thrace, while great sums of money were sent to him by Alexander. This helped to create, with Thessalian help and many mercenaries, a force double that of Agis, which Antipater in person led south in 330 BC to confront the Spartans. In the spring of that year, the two armies clashed near Megalopolis. Agis fell with many of his best soldiers, but not without inflicting heavy losses on the Macedonians.

Utterly defeated, the Spartans sued for peace; the latter's answer was to negotiate directly with the League of Corinth, but the Spartan emissaries preferred to treat directly with Alexander, who imposed on Sparta's allies a penalty of 120 talents and the entrance of Sparta in the league.

Alexander appears to have been quite jealous of Antipater's victory; according to Plutarch, the king wrote in a letter to his viceroy: "It seems, my friends that while we have been conquering Darius here, there has been a battle of mice in Arcadia".