The Consulate-General of Japan in Saint Petersburg was the consulate of Japan in Saint Petersburg, Russia. It was located at 29 Nabereznaya Reki Moiki () in the Tsentralny district of Saint Petersburg.
The building was constructed in 1851 for Aleksey Lobanov-Rostovsky, with reconstructions and extensions in 1868 and 1875.
The decision to open a consulate-general in Leningrad, as it was then named, was taken by the Japanese cabinet following a bill passed in the Diet. This happened on 30 March, 1971 with effect from April 1. This was part of a consular agreement in which consulates were also opened in Osaka, Sapporo and Nakhodka.
On June 2023, Russia ordered the closure of Japan's Consulates General in Saint Petersburg, Khabarovsk, Vladivostok and Yuzhno-Sakhalinsk as well as expelling 12 Japanese diplomats after Japan ordered the closure of Russia's Consulates General in Osaka and Sapporo