The 1980 NCAA Division I soccer tournament was the 22nd annual tournament organized by the National Collegiate Athletic Association to determine the national men's college soccer champion among its Division I members in the United States.
The final match was played at Tampa Stadium in Tampa, Florida on December 14.
San Francisco won their fourth Division I national title, defeating Indiana Hoosiers in the final, 4–3 after one overtime.
Qualifying
Three teams made their debut appearance in the NCAA Division I soccer tournament: Alabama A&M, Boston University, and William & Mary.