The 2021–22 season was Juventus Football Club's 124th season in existence and the club's 15th consecutive season in the top flight of Italian football. In addition to the domestic league, Juventus participated in this season's edition of the Coppa Italia, the Supercoppa Italiana, and the UEFA Champions League.
Juventus finished the season trophyless for the first time since 2010–11.
Season summary
Pre-season
On 11 May 2021, Gianluigi Buffon announced that he would leave Juventus at end of the previous season. On 28 May, Andrea Pirlo was sacked and Massimiliano Allegri was chosen in his place as team's coach. On 15 June, Juventus announced that Álvaro Morata's loan had been renewed.
July
On 24 July, Juventus played a friendly match against Serie C side Cesena, winning 3–1, through goals scored by Koni De Winter, Weston McKennie, and Matías Soulé. On 31 July, Juventus won their 11th Trofeo Luigi Berlusconi, winning 2–1 against Serie B side Monza at Stadio Brianteo through goals scored by Filippo Ranocchia in the 13th minute and Dejan Kulusevski in the 53rd minute.
August
On 2 August, Juventus announced that Giorgio Chiellini's contract had been renewed. On 8 August, Juventus played the Joan Gamper Trophy against Spanish La Liga side Barcelona at Johan Cruyff Stadium, losing 3–0. On 14 August, Juventus played a friendly match against Serie A side Atalanta, winning 3–1, thanks to goals scored by Paulo Dybala, Federico Bernardeschi, and Álvaro Morata. On 17 August, Juventus announced that Kaio Jorge's purchase had been officialised from Brazilian Série A side Santos. On 18 August, Juventus announced that Manuel Locatelli's purchase had been officialised from Serie A side Sassuolo. On 19 August, Juventus played the last pre-season friendly match against Serie C side Juventus U23, winning 3–0, through goals scored by Dybala, Morata, and Aaron Ramsey.
On 22 August, Juventus made their official season debut, drawing 2–2 against Udinese. Dybala scored after three minutes to the start and Juan Cuadrado doubled the result in the 23rd minute. In the 51st minute, the referee awarded a penalty kick after Juventus' goalkeeper Wojciech Szczęsny fouled Tolgay Arslan; Roberto Pereyra scored from the spot reducing the disadvantage. In the 83rd minute, Stefano Okaka scored the equalizing goal due to a Szczęsny mistake. On 28 August, Juventus lost 1–0 against Empoli in the second matchday due to a Leonardo Mancuso's goal in the 21st minute. On 31 August, Juventus announced that Cristiano Ronaldo had been sold to English Premier League side Manchester United, as well as Moise Kean's purchase from another English side, Everton.
September
On 14 September, Juventus made their debut in UEFA Champions League against Swedish side Malmö FF, winning 0–3. The match resulted in being the first season victory: in the 23rd minute, Alex Sandro scored the opening goal through a header from a Juan Cuadrado's cross; in the 45th minute, the captain Paulo Dybala scored his penalty caused by a foul on Álvaro Morata; one minute later, in the additional time, again Morata scored the third overall goal.
October
On 2 October, Juventus played the Derby della Mole against Torino side, winning 0–1. Manuel Locatelli scored the only goal late in the second half. The same result was achieved against Roma on 17 October; Moise Kean scored in the 16th minute.
On 24 October, Juventus played the Derby d'Italia against Internazionale, drawing 1–1: Paulo Dybala equalised the score on penalty late in the second half, after the first goal scored by Edin Džeko in the first period.
November
On 2 November, Juventus qualified to the knockout phase of the UEFA Champions League thanks to the 4–2 win against Russian side Zenit Saint Petersburg. Paulo Dybala scored twice, including a penalty, followed by other two goals scored by Federico Chiesa and Álvaro Morata, respectively. Zenit Saint Petersburg's goals were provided by Leonardo Bonucci's own goal and Sardar Azmoun.
December
On 8 December, Juventus achieved first position in the group stage of the UEFA Champions League with 15 points. Home win 1–0 against Malmö FF with the only goal scored by Moise Kean in the 18th minute and 3–3 between Zenit Saint Petersburg and Chelsea meant Juventus was seeded in the knockout phase round of 16 draw.