"In 1824 I had come up to London upon an errand--in itself sufficiently vexatious--of fighting against pecuniary embarrassments by literary labors; but, as always happened hitherto, with very imperfect success, from the miserable thwartings I incurred through the deranged state of the liver. My zeal was great and my application was unintermitting, but spirits radically vitiated, chiefly through the direct mechanical depression caused by one important organ deranged; and secondly, by a reflex effect of depression, through my own thoughts in estimating my prospects, together with the aggravation of my case by the inevitable exile from my own mountain home--all this reduced the value of my exertion in a deplorable way. It was rare, indeed, that I could satisfy my own judgment even tolerably with the quality of any article I produced; and my power to make sustained exertions drooped in a way I could not control, every other hour of the day; insomuch that, what with parts to be cancelled, and what with whole days of torpor and pure defect of power to produce any thing at all, very often it turned out that all my labors were barely sufficient (sometimes not sufficient) to meet the current expenses of my residence in London. Gloomy indeed was my state of mind at that period, for though I made prodigious efforts to recover my health, yet all availed me not, and a curse seemed to settle upon whatever I then undertook. One canopy of murky clouds brooded forever upon my spirits, which were in one uniformly low key of cheerless despondency."
De Quincey has given his views pretty freely as to the regimen to be observed by reforming opium-eaters, in a paper on "The Temperance Movement" which is specially worthy of attention.
"My own experience had never travelled in that course which could much instruct me in the miseries from wine or in the resources for struggling with it. I had repeatedly been obliged, indeed, to lay it aside altogether; but in this I never found room for more than seven or ten days' struggle: excesses I had never practiced in the use of wine: simply the habit of using it, and the collateral habits formed by excessive use of opium, had produced no difficulty at all in resigning it even on an hour's notice. From opium I derive my right of offering hints at all upon the subject of abstinence in other forms. But the modes of suffering from the evil, and the separate modes of suffering from the effort of self-conquest, together with errors of judgment incident to such states of transitional torment, are all nearly allied, practically analogous as regards the remedies, even if characteristically distinguished to the inner consciousness. I make no scruple, therefore, of speaking as from a station of high experience and of most watchful attention, which never remitted even under sufferings that were at times absolutely frantic. Once for all, however, in cases deeply rooted no advances ought ever to be made but by small stages; for the effect, which is insensible at first, by the tenth, twelfth, or fifteenth day generally accumulates unendurably under any bolder deduction. Certain it is, that by an error of this nature at the outset, most natural to human impatience under exquisite suffering, too generally the triai is abruptly brought to an end through the crisis of a passionate relapse.
