Plotkin () is a surname of Russian Jewish origin, which indicates a person from Plotki, a name of several villages in Russia, Belarus, and Ukraine. It may also refer to:

Alice Playten (1947–2011), born Alice Plotkin, American actress and singer

Andrew Plotkin (born 1970), American writer

Brian Plotkin (born 1984), American soccer player

Chuck Plotkin, American record producer

Diana Plotkin, American political activist

Faith Plotkin (born 1947), American writer

Gabriel Plotkin, Melvin Capital CEO

Gordon Plotkin (born 1946), British computer scientist

Gregory Plotkin, American film editor and director

Hal Plotkin (born 1957), American journalist and public servant

James Plotkin (born 1970), American guitarist

Joshua B. Plotkin, Evolutionary biologist and applied mathematician

Mark Plotkin (born 1955), American botanist

Mark Plotkin (born 1998), Canadian chess player

Stanley Plotkin (born 1932), American physician, vaccinologist, and immunologist

Tom Plotkin, American actor

See also

Plotkin bound, a mathematical limit in coding theory

14619 Plotkin, asteroid

Płotka

Surnames of Jewish origin

Russian-language surnames

Surnames of Belarusian origin

Plotkin