The 2016 Cary Challenger was a professional tennis tournament played on hard courts. It was the 2nd edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Cary, North Carolina, United States between 10 and 18 September 2016.
Singles main-draw entrants
Seeds
1 Rankings are as of August 29, 2016.
Other entrants
The following players received wildcards into the singles main draw: Nick Stachowiak Brayden Schnur Nicholas Horton Ryan Shane
The following players received entry from the qualifying draw: James McGee Mackenzie McDonald Ryan Haviland Erik Crepaldi
Champions
Singles
James McGee def. Ernesto Escobedo, 1–6, 6–1, 6–4.
Doubles
Philip Bester / Peter Polansky def. Austin Krajicek / Stefan Kozlov, 6–2, 6–2.