Saint Lucia competed at the 2022 Commonwealth Games at Birmingham, England from 28 July – 8 August 2022. It was the team's 11th appearance at the Games.
On July 23, 2022, a team of 13 athletes (ten men and three women) competing in four sports was named. Arthur Langelier and Julien Alfred were the country's flagbearers during the opening ceremony.
Medalists
Competitors
The following is the list of number of competitors participating at the Games per sport/discipline.
Athletics
Men
Track and road events
Field events
Women
Track and road events
Field events
Boxing
A squad of three boxers was entered as of 9 July 2022.
Men
Swimming
Table tennis
Withdrawn sport
3x3 basketball
By virtue of its status as the top Commonwealth Caribbean nation in the FIBA 3x3 Federation Rankings for women (on 1 November 2021), Saint Lucia was originally invited to play in the women's tournament. However, the basketball federation declined the invitation on account of not being able to send an adequately prepared squad to the Games.