Meanwhile Henry had been developing a serious interest in politics, and he could brook no superior in whatever sphere he wished to shine. He began to adopt a more critical attitude towards Wolsey's policy, foreign and domestic; and to give ear to the murmurs against the cardinal and his ecclesiastical rule. Parliament had been kept at arm's length since 1515 lest it should attack the church; but Wolsey's expensive foreign policy rendered recourse to parliamentary subsidies indispensable. When it met in 1523 it refused Wolsey's demands, and forced loans were the result which increased the cardinal's unpopularity. Nor did success abroad now blunt the edge of domestic discontent. His fate, however, was sealed by his failure to obtain a divorce for Henry from the papal court. The king's hopes of male issue had been disappointed, and by 1526 it was fairly certain that Henry could have no male heir to the throne while Catherine remained his wife. There was Mary, but no queen regnant had yet ruled in England; Margaret Beaufort had been passed over in favour of her son in 1485, and there was a popular impression that women were excluded from the throne. No candidate living could have secured the succession without a recurrence of civil war. Moreover the unexampled fatality which had attended Henry's issue revived the theological scruples which had always existed about the marriage; and the breach with Charles V. in 1527 provoked a renewal of the design of 1514. All these considerations were magnified by Henry's passion for Anne Boleyn, though she certainly was not the sole or the main cause of the divorce. That the succession was the main point is proved by the fact that Henry's efforts were all directed to securing a wife and not a mistress. Wolsey persuaded him that the necessary divorce could be obtained from Rome, as it had been in the case of Louis XII. of France and Margaret of Scotland. For a time Clement VII. was inclined to concede the demand, and Campeggio in 1528 was given ample powers. But the prospect of French success in Italy which had encouraged the pope proved delusive, and in 1529 he had to submit to the yoke of Charles V. This involved a rejection of Henry's suit, not because Charles cared anything for his aunt, but because a divorce would mean disinheriting Charles's cousin Mary, and perhaps the eventual succession of the son of a French princess to the English throne.