The American live-action/animated 2001 film Osmosis Jones features a variety of fictional characters created by Marc Hyman. It followed up with American animated television series Ozzy & Drix which originally aired on Kids' WB from 2002 to 2004, shows a white blood cell police officer team up with a cold pill to defeat many germs and viruses. The series had twenty-six episodes in two seasons.
Main characters
Osmosis "Ozzy" Jones
Voiced By Chris Rock (film), Phil LaMarr (series)
Osmosis Jones is a white blood cell cop who wants to track down germs and viruses.
Drixenol "Drix" Koldreliff
Voiced By David Hyde Pierce (film), Jeff Bennett (series)
Drix is a cold pill and Ozzy's best friend and partner that is designed to soothe irritation within the cities of Frank and Hector.
Allies
Leah Estrogen
Voiced By Brandy Norwood
Leah Estrogen is the secretary of the mayor of Frank. She is romantic interest to Osmosis Jones who agreed with her on making changes to Frank's lifestyle choices.
Maria Amino
Voiced by Tasia Valenza
Maria Amino is a female Hispanic white blood cell cop who is highly skilled at fighting and the replacement for Leah. Despite showing her midriff, she's not drawn with a belly button. She also appears to have a crush on Drix.
Tom Colonic
Voiced By Ron Howard
Tom Colonic was the political opponent of Charles Phlegmming who wanted to be the next mayor of Frank so that the city will be healthy from a better diet. After Ozzy and Drix defeated Thrax and prevented his plan to kill Frank, resulting in Phlegmming's impeachment, he eventually won the bid for the mayor of Frank in a landslide. However, it is implied that he got impeached thanks to Frank's relapse to his unhealthy diet.
Mayor Paul Spryman
Voiced By Alanna Ubach
Mayor Paul Spryman is the teenage mayor of the City of Hector. His being a teenage boy is a reflection of the fact that Hector is a teenage boy.
Ellen Patella
Voiced by Vivica A. Fox
Ellen Patella is the attorney-at-law and helps cells find homes in the City of Hector. She, like Leah and Maria respectively, also seems like someone Osmosis takes a romantic interest in.
Cilia Tyson
Voiced by Dawnn Lewis
Cilia Tyson is a cop in Christine who helped Ozzy stop the Pneumoniac and prove that Maximus is a traitor to the city. She was made the new police chief by the mayor.
Mayor Conscious Santorini
Voiced by Cree Summer
Mayor Conscious Santorini is the mayor of Christine, and she is more smart and responsible than Spryman. She even said that everyone in Christine are fans of Hector.
Drixeen
Voiced by Miriam Flynn
Drixeen is a friend to Cilia and she used to a cold pill. She looks a bit like Drix except she's green instead of red, has hair, and a right hand and left cannon, while Drix is red, has no hair, and his arm positions are the other way.
Dander
Vocal Effects By Frank Welker
Dander is a dog germ formed from the saliva of Hector's dog Uno and Drix's pet.
Police chiefs
Chief
Voiced by Joel Silver (uncredited)
The Chief is Ozzy's boss in the City of Frank.
Chief Gluteus
Voiced by Jim Cummings
Chief Gluteus is a gruff old muscle cell and the police chief of the City of Hector. He has a burning hatred for Ozzy and Drix.