The following list includes notable people from the city of Nablus.
Modern era
Yoseph ben Ab-Hisda ben Yaacov ben Aaharon (1919–1998), former Samaritan high priest Awni Abd al-Hadi (1889–1970), 20th century Palestinian politician. Rabab Abdulhadi (born 1955), Palestinian-born American scholar, activist, educator, editor, and an academic director. Hani Awijan (1977–2016), former head of the Palestinian Islamic Jihad militant group in Nablus. Nasib al-Bitar (1890–1948), former Islamic court judge. Izzat Darwaza (1888–1984), Palestinian Arab nationalist leader in early 20th century. Aziz Dweik (born 1948), Speaker of the Palestinian Legislative Council. Mohamed Ali Eltaher (1896–1974), Palestinian journalist and newspaper editor. Fadi Kafisha (1977–2006), former head of Tanzim militant group in Nablus. Sahar Khalifeh (born 1941), Palestinian writer. Munib Masri (born 1934), Palestinian billionaire. Ahmed Sheikh (born 1949), editor-in-chief of Al-Jazeera. Ahmad Toukan (1903–1981), late Prime Minister and educator. Fadwa Touqan (1917–2003), Palestinian poet. Fawwaz Tuqan (born 1940), writer, professor and former minister. Ibrahim Touqan (1905–1941), Palestinian poet. Abdel Wael Zwaiter (1934–1972), translator.
Pre-modern period
Ibn al-Sal'us (died 1294), a 13th-century merchant and Mamluk vizier
Justin Martyr (c. AD 100 – c. AD 165), second century Christian apologist
Muhammad ibn Ahmad al-Nabulusi - anti-Fatimid rebel who moved to Baniyas to continue his agitation against the Fatimid Caliphate