This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.
The agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone.
Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.
Alkylating agents
Altretamine
Bendamustine
Busulfan
Carboquone
Carmustine
Chlorambucil
Chlormethine
Chlorozotocin
Cyclophosphamide
Dacarbazine
Fotemustine
Ifosfamide
Lomustine
Melphalan
Melphalan flufenamide
Mitobronitol
Nimustine
Nitrosoureas
Pipobroman
Ranimustine
Semustine
Streptozotocin
Temozolomide
Thiotepa
Treosulfan
Triaziquone
Triethylenemelamine
Trofosfamide
Uramustine
Anthracyclines
Aclarubicin
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mitoxantrone
Pirarubicin
Valrubicin
Zorubicin
Cytoskeletal disruptors (taxanes)
Abraxane
Cabazitaxel
Docetaxel
Larotaxel
Paclitaxel
Taxotere
Tesetaxel
Epothilones
Ixabepilone
Histone deacetylase inhibitors
Entinostat
Romidepsin
Vorinostat
Zabadinostat
Inhibitors of topoisomerase I
Belotecan
Camptothecin
Exatecan
Gimatecan
Irinotecan
Topotecan
Inhibitors of topoisomerase II
Etoposide
Teniposide
Tafluposide
Kinase inhibitors
Bortezomib
Erlotinib
Gefitinib
Imatinib
Vemurafenib
Vismodegib
Nucleotide analogs and precursor analogs
Azacitidine
Azathioprine
Capecitabine
Cytarabine
Doxifluridine
Fluorouracil
Gemcitabine
Hydroxyurea
Mercaptopurine
Methotrexate
Tioguanine (formerly Thioguanine)