Jefferson County Jail, also known as Jefferson County Jail and Sheriffs House, is a historic jail and residence located at Madison, Jefferson County, Indiana. It was built between 1848 and 1850, and is a two-story, rectangular Greek Revival style masonry building. The building consists of two blocks: a residential section in front and jail block at the rear. A kitchen wing was added in 1859. It features a classic pedimented gable temple front with a recessed entrance and pilasters.
It was listed on the National Register of Historic Places in 1973. It is located in the Madison Historic District.