Khadija Ciss (born March 26, 1983) is a Senegalese former swimmer, who specialized in long-distance freestyle events. She won a bronze medal in the 200 m freestyle at the 2003 All-Africa Games in Abuja, Nigeria (2:09.00).
Ciss qualified for two swimming events at the 2004 Summer Olympics in Athens, by achieving FINA B-standard entry times of 2:05.51 (200 m freestyle) and 9:02.54 (800 m freestyle) from the EDF Swimming Open in Paris. In the 200 m freestyle, Ciss challenged five other swimmers on the second heat, including two-time Olympian Vesna Stojanovska of Macedonia. She rounded out the field to last place and fortieth overall by a 4.42-second margin behind winner Jana Myšková of the Czech Republic in 2:09.04. In her second event, 800 m freestyle, Ciss ended her Olympic run in twenty-ninth place with a slowest time of 9:20.06.