The Seattle Mariners 2006 season was their 30th since the franchise creation, and their third consecutive season finishing at the bottom of the American League West, finishing with a record.
Two players were featured in the All-Star Game: Ichiro Suzuki, making his sixth appearance in the All-Star Game, and José López, with his first appearance.
The Mariners' longest winning streak was 5 games, which they managed twice, between and counterpointed by their longest losing streak of 11 games from
Offseason
December 7, 2005: Yorvit Torrealba was traded by the Seattle Mariners to the Colorado Rockies for Marcos Carvajal. January 9, 2006: Cody Ransom was signed as a free agent with the Seattle Mariners. March 30, 2006: Cody Ransom was purchased by the Houston Astros from the Seattle Mariners.
Regular season
Season standings
Record vs. opponents
Notable transactions
July 26, 2006: Ben Broussard was traded by the Cleveland Indians with cash to the Seattle Mariners for a player to be named later and Shin-Soo Choo. The Seattle Mariners sent Shawn Nottingham (minors) (August 24, 2006) to the Cleveland Indians to complete the trade.
Roster
Game log
|- style="background-color:#ffbbbb" | 1 || April 3 || Angels || 5–4 || Shields (1–0) || Sherrill (0–1) || Rodríguez (1) || 45,515 || 0–1 |- style="background-color:#bbffbb" | 2 || April 4 || Angels || 10–8 || Piñeiro (1–0) || Lackey (0–1) || || 20,051 || 1–1 |- style="background-color:#bbffbb" | 3 || April 5 || Angels || 6–4 || Washburn (1–0) || Weaver (0–1) || Sherrill (1) || 21,394 || 2–1 |- style="background-color:#bbffbb" | 4 || April 6 || Athletics || 6–2 || Meche (1–0) || Loaiza (0–1) || Putz (1) || 22,701 || 3–1 |- style="background-color:#ffbbbb" | 5 || April 7 || Athletics || 5–0 || Blanton (1–0) || Hernández (0–1) || || 30,612 || 3–2 |- style="background-color:#ffbbbb" | 6 || April 8 || Athletics || 3–0 || Zito (1–1) || Moyer (0–1) || Street (1) || 37,904 || 3–3 |- style="background-color:#ffbbbb" | 7 || April 9 || Athletics || 6–4 || Harden (1–0) || Piñeiro (1–1) || Street (2) || 27,139 || 3–4 |- style="background-color:#ffbbbb" | 8 || April 11 || @ Indians || 9–5 || Lee (1–0) || Washburn (1–1) || || 17,559 || 3–5 |- style="background-color:#bbffbb" | 9 || April 12 || @ Indians || 11–9 || Woods (1–0) || Byrd (1–1) || Guardado (1) || 14,773 || 4–5 |- style="background-color:#bbffbb" |10 || April 13 || @ Indians || 9–5 || Mateo (1–0) || Sauerbeck (0–1) || Putz (2) || 24,638 || 5–5 |- style="background-color:#ffbbbb" | 11 || April 14 || @ Red Sox || 2–1 || Schilling (3–0) || Moyer (0–2) || Papelbon (5) || 36,431 || 5–6 |- style="background-color:#bbffbb" | 12 || April 15 || @ Red Sox || 3–0 || Piñeiro (2–1) || Wakefield (1–2) || Guardado (2) || 36,047 || 6–6 |- style="background-color:#ffbbbb" | 13 || April 16 || @ Red Sox || 3–2 || Beckett (3–0) || Washburn (1–2) || Papelbon (6) || 36,181 || 6–7 |- style="background-color:#ffbbbb" | 14 || April 17 || @ Red Sox || 7–6 || Timlin (1–0) || Guardado (0–1) || || 36,188 || 6–8 |- style="background-color:#ffbbbb" | 15 || April 18 || Rangers || 7–4 || Koronka (2–1) || Hernández (0–2) || Cordero (2) || 17,927 || 6–9 |- style="background-color:#bbffbb" | 16 || April 19 || Rangers || 9–6 || Putz (1–0) || Cordero (1–2) || || 17,613 || 7–9 |- style="background-color:#ffbbbb" | 17 || April 20 || Rangers || 4–3 || Bauer (1–0) || Guardado (0–2) || Cordero (3) || 17,917 || 7–10 |- style="background-color:#ffbbbb" | 18 || April 21 || Tigers || 2–1 || Maroth (3–0) || Washburn (1–3) || Jones (1) || 35,237 || 7–11 |- style="background-color:#ffbbbb" | 19 || April 22 || Tigers || 2–0 || Robertson (2–2) || Meche (1–1) || Rodney (4) || 27,893 || 7–12 |- style="background-color:#ffbbbb" | 20 || April 23 || Tigers || 6–4 || Verlander (2–2) || Hernández (0–3) || Jones (2) || 28,659 || 7–13 |- style="background-color:#bbffbb" | 21 || April 24 || White Sox || 4–3 || Mateo (2–0) || McCarthy (1–1) || || 20,390 || 8–13 |- style="background-color:#ffbbbb" | 22 || April 25 || White Sox || 13–3 || Vázquez (2–1) || Piñeiro (2–2) || Logan (1) || 20,451 || 8–14 |- style="background-color:#bbffbb" | 23 || April 26 || White Sox || 5–1 || Washburn (2–3) || Buehrle (3–1) || || 23,848 || 9–14 |- style="background-color:#ffbbbb" | 24 || April 28 || @ Orioles || 5–2 || Cabrera (2–2)|| Meche (1–2) || Ray (7) || 26,934 || 9–15 |- style="background-color:#bbffbb" | 25 || April 29 || @ Orioles || 8–6 || Hernández (1–3) || Brower (0–1)|| Guardado (3) || 34,161 || 10–15 |- style="background-color:#bbffbb" | 26 || April 30 || @ Orioles || 4–3 || Moyer (1–2) || López (1–3) || Guardado (4) || 32,421 || 11–15