The 2016 San Antonio Open was a professional tennis tournament played on outdoor hard courts. It was the 1st edition of the tournament as part of the 2016 WTA 125K series. It took place in San Antonio, United States, on 12–19 March 2016.
Singles entrants
Seeds
1 Rankings as of 7 March 2016.
Other entrants
The following players received wildcards into the singles main draw: Irina-Camelia Begu Catherine Bellis Casey Dellacqua Daria Gavrilova Teliana Pereira Maria Sakkari
Withdrawals
Before the tournament
Karin Knapp →replaced by Lauren Davis
Bojana Jovanovski →replaced by Naomi Broady
Doubles entrants
Seeds
1 Rankings as of 7 March 2016.
Other entrants
The following pair received a wildcard into the doubles main draw: Ashley Weinhold / Caitlin Whoriskey
Champions
Singles
Misaki Doi def. Anna-Lena Friedsam, 6–4, 6–2
Doubles
Anna-Lena Grönefeld / Nicole Melichar def. Klaudia Jans-Ignacik / Anastasia Rodionova, 6–1, 6–3