The 2022 Internationaux de Tennis de Vendée was a professional tennis tournament played on hard courts. It was the ninth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Mouilleron-le-Captif, France between 3 and 9 October 2022.
Singles main-draw entrants
Seeds
1 Rankings are as of 26 September 2022.
Other entrants
The following players received wildcards into the singles main draw: Arthur Fils Vasek Pospisil Clément Tabur
The following players received entry into the singles main draw as alternates: Arthur Cazaux Vitaliy Sachko
The following players received entry from the qualifying draw: Mathias Bourgue Jurgen Briand Alexis Gautier Jules Marie David Poljak Valentin Royer
The following player received entry as a lucky loser: Kenny de Schepper
Champions
Singles
Jelle Sels def. Vasek Pospisil 6–4, 6–3.
Doubles
Sander Arends / David Pel def. Purav Raja / Divij Sharan 6–7(1–7), 7–6(8–6), [10–6].