The Eli Rayner House is a historic house in Memphis, Tennessee, U.S.. It was built in 1856 for Eli Rayner, a planter, and his wife May A. Jones. The Rayner were well-connected: Rayner's first cousin was Kenneth Rayner, and their daughter Irene married Thomas B. Turley.
The house is a relatively sophisticated Late Greek Revival-style building, with "elegantly proportioned fluted columns capped with lotus leaf Corinthian capitals, supporting the pediment with simple scrolled triglyphs...." A cast-iron balcony, original or from before 1900, is at the second floor level within the two-story portico.
The house has been listed on the National Register of Historic Places since May 9, 1977.