Nájera is a surname. Notable people with the surname include:

Antonio Vallejo-Nájera (1889–1960), Spanish psychiatrist

Ariel Castillo Nájera (born 1955), Mexican politician

Carlos Antonio Reyes Nájera (born 1961), Guatemalan chess player

Eduardo Nájera (born 1976), Mexican basketball player

Elisa Nájera (born 1986), Mexican TV host, model and beauty pageant titleholder

Francisco Nájera (born 1983), Colombian footballer

Fredy Renán Nájera (born 1977), Honduran politician

José Manuel Nájera (born 1988), Colombian footballer

Juan Carlos Nájera (born 1981), Guatemalan triple jumper and coach

Lourdes Gutiérrez Nájera, American cultural anthropologist

Manuel Nájera (born 1952), Mexican footballer

Manuel Gutiérrez Nájera (1859–1895), Mexican writer and political figure

Maricruz Nájera, Mexican actress

Oscar Ramón Nájera (born 1950), Honduran politician

Pedro Nájera (1929–2020), Mexican footballer

Rosa María Avilés Nájera (born 1951), Mexican politician

Rossana Nájera (born 1980), Mexican actress

Nájera (surname)