The Buffalo Hotel in Garden City, Kansas, was built in 1886. It was listed on the National Register of Historic Places in 2008.
It is a masonry building with limestone exterior. Its front, South-facing facade is wide and is divided into five bays. It was designed by architects J.H. Stevens and C.L. Thompson in Italianate style.
It was deemed significant "for its association with the early history of Garden City (pop. 28,451) and as a nineteenth century hotel, ...for its association with town founder and western legend Charles Jesse (Buffalo) Jones, and ...as an example of Italianate commercial architecture."