After making several abortive attempts of this kind, I tried at last the substitution of laudanum for alcohol. It was a most fatal move! for the final result was a bondage of which previously I had not even a conception. At first, however, I seemed as though lifted out of the pit into Paradise. Instead of the feverish, tumultuous excitement of alcohol, I experienced a calm, equable, thrilling enjoyment. My whole being was exalted from its previous turmoil and perturbation and heat, to dwell in a region of serenity and peace and quiet bliss. But alas for the reverse side of the picture! The total prostration, the depth of depression, the more than infantile feebleness following the reaction of this excitement--the multitude of uneasy, uncomfortable, often bewildering sensations pertaining to the habit, are such as can not be conveyed to one inexperienced in the matter. But any one may decide that the presence and incorporation with the system, in large quantities, of a poison which is so deadly a foe to life and all life's movements can not be without very marked and baneful results. The fact is that there is not one out of the thousand various functions of the body which is not deranged and turned away by this cause, and the movements of the mind and heart are from sympathy hardly less morbid. Whether such a state must not be one of sufferings many, and often frightful, every one may judge.
But worse even than this followed. It was not very long before the opium nearly lost its power to excite and enliven, though it still kept an inexorable clutch on every fibre of my frame, and I was compelled to take it daily to keep the very current of life flowing.
To make my condition worse still, while obliged to use opium daily to prolong even this existence--gloomy and apathetic as it was--I found that in order to think or work with any thing of vigor I absolutely required, every now and then, some excitement which opium now would not give. I tried, therefore, strong tea and coffee and tobacco-smoking. But all these were not enough, and I found there was nothing for me but to try alcohol again; so that the upshot of my experiment of substituting opium for alcohol was, that I got opium, alcohol, tea, coffee, and tobacco-smoking fastened upon me all at once and all in excessive quantities; and the consequence of using alcohol was that no caution I could employ would secure me from occasional intoxication. Such was my physical derangement that I never could be certain beforehand of the degree of effect which alcoholic stimulus would exert upon me, and the same quantity which at one time would produce only the excitement I sought, would under other physical conditions completely overcome me.