Matson Street Historic District is a national historic district located at Kershaw, Lancaster County, South Carolina. It encompasses 26 contributing buildings in a residential section of Kershaw. The majority of the buildings date from about 1890 to 1940, a particularly significant period of development in Kershaw. The houses are in a variety of representative architectural styles include Victorian, Queen Anne, Bungalow, American Craftsman, Colonial Revival, and Neo-Classical. Also located in the district is the First Presbyterian Church.
It was added to the National Register of Historic Places in 1990.