The 2004–2005 Sta. Lucia Realtors season was the 12th season of the franchise in the Philippine Basketball Association (PBA).
Draft picks
Roster
Philippine Cup
Game log
|- bgcolor="#edbebf" | 1 | October 7 | San Miguel | 73–79 | | | | Zamboanga City | 0–1 |- bgcolor="#edbebf" | 2 | October 10 | Brgy.Ginebra | 84–88 | Espino (22) | | | Araneta Coliseum | 0–2 |- bgcolor="#edbebf" | 3 | October 15 | Shell | 78–84 | Duremdes (18) Espino (18) | | | Philsports Arena | 0–3 |- bgcolor="#edbebf" | 4 | October 22 | Purefoods | 87–89 | Duremdes (37) | | | Philsports Arena | 0–4 |- bgcolor="#edbebf" | 5 | October 26 | Red Bull | 118–124 (3OT) | | | | Bacolod | 0–5
|- bgcolor="#edbebf" | 6 | November 3 | Alaska | | | | | Araneta Coliseum | 0–6 |- bgcolor="#bbffbb" | 7 | November 7 | Coca Cola | 86–69 | | | | Araneta Coliseum | 1–6 |- bgcolor="#bbffbb" | 8 | November 12 | FedEx | | Mendoza (35) | | | Cuneta Astrodome | 2–6 |- bgcolor="#edbebf" | 9 | November 16 | Brgy.Ginebra | 79–85 | | | | Cavite City | 2–7 |- bgcolor="#edbebf" | 10 | November 19 | San Miguel | 74–95 | | | | | 2–8 |- bgcolor="#bbffbb" | 11 | November 24 | Coca Cola | 98–92 | Duremdes (24) | Espino (8) | Espino (6) | Araneta Coliseum | 3–8 |- bgcolor="#bbffbb" | 12 | November 30 | Talk 'N Text | 104–102 | Duremdes (34) Aquino (29) | | | Puerto Princesa | 4–8
|- bgcolor="#edbebf" | 13 | December 5 | Shell | 83–84 | Aquino (23) | | | Araneta Coliseum | 4–9 |- bgcolor="#bbffbb" | 14 | December 10 | Purefoods | 91–89 | | | | Araneta Coliseum | 5–9 |- bgcolor="#edbebf" | 15 | December 15 | FedEx | 104–114 | | | | Araneta Coliseum | 5–10 |- bgcolor="#edbebf" | 16 | December 19 | Talk 'N Text | 83–102 | Espino (23) | | | Makati Coliseum | 5–11 |- bgcolor="#bbffbb" | 17 | December 22 | Red Bull | 105–84 | Duremdes (27) | | | Philsports Arena | 6–11
|- bgcolor="#edbebf" | 18 | January 5 | Alaska | 95–105 | Duremdes (29) | | | Philsports Arena | 6–12