Brian M. Hoffman (born August 7, 1941 in Chicago) is an American bioinorganic and physical chemist.
Career
Hoffman is a graduate of Lane Tech High School in Chicago and then studied chemistry at the University of Chicago receiving a bachelor's degree in 1962 and at Caltech with a PhD in chemistry in 1966 under the direction of Harden M. McConnell. Hoffman was briefly a postdoctoral scholar with Alexander Rich at MIT. In 1967 he started his appointment at Northwestern University, where he has remained throughout his career.
Research and recognition
Using electron-nuclear double-resonance (ENDOR) spectroscopy, Hoffman has investigated many enzyme mechanisms. Subject of this work include nitric oxide synthase, cytochrome P450, nickel-iron hydrogenase, and nitrogenase.
In 2012, he received the Joseph Chatt Award, in 2013 the F. A. Cotton Medal. He also received the Bruker Award He is a member of the National Academy of Sciences (2006), the American Academy of Arts and Sciences (2002) and the American Association for the Advancement of Science (1983). He was a Sloan Fellow.