Route 205 or Highway 205 may refer to:
Canada
Manitoba Provincial Road 205
New Brunswick Route 205
Newfoundland and Labrador Route 205
Nova Scotia Route 205
Prince Edward Island Route 205
Quebec Route 205
China
China National Highway 205
Costa Rica
National Route 205
India
National Highway 205 (India)
Japan
Japan National Route 205
Thailand
Thailand Route 205 (Suranarai Road)
United States
Interstate 205
Alabama State Route 205
Connecticut Route 205
Florida State Road 205 (former) Georgia State Route 205 (former) Indiana State Road 205 Iowa Highway 205 (former) K-205 (Kansas highway) Kentucky Route 205 Maine State Route 205 M-205 (Michigan highway) (former) Montana Secondary Highway 205 New Mexico State Road 205 New York State Route 205 North Carolina Highway 205 Ohio State Route 205 Oregon Route 205 Pennsylvania Route 205 (former) Tennessee State Route 205 Texas State Highway 205 Texas State Highway Loop 205 Utah State Route 205 (former) Virginia State Route 205 Territories Puerto Rico Highway 205