Jamestown High School, Former, also known as Jamestown Public School, is a historic school building located at Jamestown, Guilford County, North Carolina. It was designed by architect Charles E. Hartge and built in 1915. It is a 2 1/2-story, Classical Revival style brick building with cast stone detailing. It features a full-height tetrastyle entrance portico supported by Ionic order columns and pilasters. The building underwent a major rehabilitation and adaptive reuse in 1986 and 1987.
It was listed on the National Register of Historic Places in 1991.