Perrin Busbee (February 10, 1872 – January 9, 1935) was an American football and baseball coach. He served as the head football coach at North Carolina College of Agriculture and Mechanic Arts, now North Carolina State University, in 1892 again from 1896 to 1897, compiling a record of 3–2. Busbee was also the first head baseball coach at the University of North Carolina at Chapel Hill, coaching from 1891 to 1893 and tallying a mark of 9–6.
On Jan. 9, 1935, he died in Raleigh and is buried in Oakwood Cemetery.