The 2021–22 season was the 114th season in the existence of Real Betis and the club's seventh consecutive season in the top flight of Spanish football. In addition to the domestic league, Real Betis participated in this season's editions of the Copa del Rey and the UEFA Europa League.
Players
First-team squad
.
Reserve team
Out on loan
Transfers
In
Out
Pre-season and friendlies
Competitions
Overall record
La Liga
League table
Results summary
Results by round
Matches
The league fixtures were announced on 30 June 2021.
Copa del Rey
UEFA Europa League
Group stage
The draw for the group stage was held on 27 August 2021.
Knockout phase
Knockout round play-offs
The knockout round play-offs draw was held on 13 December 2021.
Round of 16
The draw for the round of 16 was held on 25 February 2022.
Statistics
Appearances and goals
Last updated 20 May 2022.
|-
! colspan=14 style=background:#dcdcdc; text-align:center|Goalkeepers
|-
! colspan=14 style=background:#dcdcdc; text-align:center|Defenders
|-
! colspan=14 style=background:#dcdcdc; text-align:center|Midfielders
|-
! colspan=14 style=background:#dcdcdc; text-align:center|Forwards
|-
! colspan=14 style=background:#dcdcdc; text-align:center| Players who have made an appearance or had a squad number this season but have left the club either permanently or on loan