The 2018 Visit Panamá Cup was a professional tennis tournament played on clay courts. It was the fifth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Panama City, Panama between 2 and 7 April 2018.
Singles main-draw entrants
Seeds
1 Rankings are as of 19 March 2018.
Other entrants
The following players received wildcards into the singles main draw: Emilio Gómez José Gilbert Gómez Sebastian Korda Renzo Olivo
The following players received entry into the singles main draw as alternates: Andrea Basso Rubin Statham
The following player received entry into the singles main draw as a special exempt: Pedro Sakamoto
The following players received entry from the qualifying draw: Juan Ignacio Londero Cristian Rodríguez Evan Song Peter Torebko
The following player received entry as a lucky loser: Felipe Mantilla
Champions
Singles
Carlos Berlocq def. Blaž Rola 6–2, 6–0.
Doubles
Yannick Hanfmann / Kevin Krawietz def. Nathan Pasha / Roberto Quiroz 7–6(7–4), 6–4.