José Hernández may refer to:
Arts and éHernáentertainment
José Hernández (writer) (1834–1886), Argentine writer
Pepe Hern (José Hernández Bethencourth, 1927–2009), American actor
José Hernández, American singer (born 1940), better known as Little Joe
José Hernández (painter) (1944–2013), Spanish painter
José Hernández (musician) (born 1958), Mexican musician
Chef Pepín (José Hernández), Cuban-born, American TV cook
Politicians
José Conrado Hernández (1849–1932), Chief Justice of the Supreme Court of Puerto Rico José Manuel Hernández (1853–1921), Venezuelan caudillo, army general and politician José Alarcón Hernández (born 1945), Mexican politician José María Hernández (1959–2015), Spanish politician
Science and academia
José Gregorio Hernández (1864–1919), Venezuelan physician
José M. Hernández (born 1962), American astronaut
Sportspeople
Association football
Cheche Hernández (born 1956), Colombian football manager
José Hernández (footballer, born 1961), Venezuelan football manager and former footballer José Alberto Hernández (born 1977), Mexican football midfielder José Hernández (footballer, born 1994), Mexican football midfielder José Romario Hernández (born 1994), Mexican football winger José Antonio Hernández (born 1995), Mexican football midfielder José Hernández (footballer, born 1996), Mexican football midfielder José Hernández (footballer, born 1997), Venezuelan football left-back for La Equidad José Santiago Hernández (born 1997), Mexican football goalkeeper José Hernández (soccer, born 2000), Canadian soccer forward