Buttermilk Creek may refer to:
In Canada
Buttermilk Creek (Renfrew County), a tributary of the Muskrat River in the township of Whitewater Region, Ontario Buttermilk Creek (Lambton County), a tributary of Stonehouse Drain in the town of Petrolia, Ontario
In the United States
Buttermilk Creek Complex, an archaeological site west of Salado, Texas
A creek in Buttermilk Falls State Park, southwest of Ithaca, New York
A tributary of Cattaraugus Creek, in western New York
A stream in Alpha, Wisconsin
A park in Fond du Lac, Wisconsin
A tributary of Sweetwater Creek (Chattahoochee River), in Georgia
A stream that runs through Robinson Township, Brown County, Kansas
Buttermilk Creek (Susquehanna River) Buttermilk Creek (Cayuga Inlet), a tributary of Cayuga Inlet in New York