This list is complete and up-to-date as of May 11, 2023. The following is a list of players, both past and current, who appeared at least in one game for the San Diego Padres National League franchise (1969–present).

Players in Bold are members of the National Baseball Hall of Fame.

San Diego Padres all-time roster

Players in Italics have had their numbers retired by the team.

San Diego Padres all-time roster

A

Shawn Abner

CJ Abrams

Ed Acosta

Austin Adams

Mike Adams

Jon Adkins

Sergio Alcántara

Mike Aldrete

Manny Alexander

Jorge Alfaro

Eliézer Alfonzo

Austin Allen

Dusty Allen

Greg Allen

Logan Allen

Carlos Almanzar

Bill Almon

Abraham Almonte

Roberto Alomar

Sandy Alomar Jr. Yonder Alonso Matty Alou Dan Altavilla Gabe Alvarez R. J. Alvarez Alexi Amarista Chip Ambres Héctor Ambriz Larry Andersen Dwain Anderson Shaun Anderson John Andreoli Matt Antonelli José Arcia Oswaldo Arcia Alex Arias George Arias Steve Arlin Mike Armstrong Jake Arrieta Randy Asadoor Andy Ashby Tucker Ashford Pedro Astacio Carlos Asuaje Rich Aurilia Brad Ausmus Pedro Ávila Erick Aybar José Azócar Oscar Azócar

San Diego Padres all-time roster