Manuel is a male given name originating in the Hebrew name Immanu'el (, which means "God with us.") It was reportedly brought from the Byzantine Empire (as ) to Europe, mainly to Germany, Portugal and Spain, where it has been used since at least the 13th century. The name is popular in Spanish, Portuguese, German, French, Romanian, Greek (latinized as Manouilidis), Polish and Dutch, where Manny or Manu are used as nicknames.
Middle Ages
Manuel I Komnenos (1118–1180) Manuel II Palaiologos (1350–1425) Manuel I of Trebizond (1218–1263) Manuel II of Trebizond (1324–1333) Manuel III of Trebizond (1364–1417) Manuel I of Portugal (1469–1521) Infante Manuel, Count of Ourém, Portuguese prince, son of Peter II of Portugal Manuel of Castile (1234–1283), son of Ferdinand III of Castile Manuel I, patriarch of Constantinople in 1216–22 Manuel II, patriarch of Constantinople in 1244–55 Manuel Christonymos, birth name of Patriarch Maximus III of Constantinople, reigned 1476–1482
Early modern
Manuel da Nóbrega (1517–1570), Portuguese Jesuit and missionary in the early Colonial Brazil Manuel, Prince of Portugal (1531–1537), son of John III of Portugal Manuel Maria Barbosa du Bocage (1765–1805), Portuguese poet Manuel Cardoso (composer) (1566–1650), Portuguese composer Manuel Belgrano (1770–1820), Argentine politician and military leader during the Argentine War of Independence Manuel Pardo (politician) (1834-1878), Peruvian politician Manuel Pinto da Fonseca (1681–1773), Portuguese nobleman and Grand Master of the Order of Malta