Mathiesen is a Danish-Norwegian patronymic surname meaning "son of Mathies" (equivalent of the Biblical Μαθθαιος, cf. English Matthew). Several spelling variants are used, including Matthiesen, Matthiessen, Mathisen, Matthisen. A similar diversity of forms exist for the parallel given name Mathias. There are several people with the surname Mathiesen:
Árni Mathiesen (born 1958), Icelandic politician
Børge Mathiesen (1918–1962), Danish football player
Brian Vad Mathiesen, (born 1978), Danish engineer and professor
Charles Mathiesen (1911–1994), Norwegian speed skater
Mathiesen family, a Norwegian business family, including
Christian Pierre Mathiesen (1870–1953), Norwegian politician for the Conservative Party Haagen Mathiesen (1759–1842), Norwegian timber merchant, ship-owner and politician. Haaken C. Mathiesen (1827–1913), Norwegian landowner and businessperson Haaken L. Mathiesen (1858–1930), Norwegian landowner and businessperson Jørgen Mathiesen (1901–1993), Norwegian landowner and businessperson Hein-Arne Mathiesen (born 1971), Norwegian ski jumper Mattis Mathiesen (1924–2010), Norwegian photographer and film director Mihkel Mathiesen (1918–2003), Estonian politician Niels Mathiesen (1829–1900), Norwegian politician and merchant Pål Mathiesen (born 1977), Norwegian musician Per Mathiesen (1885–1971), Norwegian gymnast Thomas Mathiesen (1933–2021), Norwegian sociologist
Matthiesen may refer to: