I have met with several cases in the course of my dissections, in which the liver was found smaller than natural, shrivelled, indurated, its blood-vessels diminished in size and number, with the whole of its internal structure more or less changed. In consequence of these morbid changes in the liver, other organs become affected, as the spleen, the pancreas, etc., either by sympathy or in consequence of their dependence on the healthy functions of the liver for the due performance of their own.
6. Of _the brain_ and its functions. Inflammation and engorgement of this organ are frequent consequences of intemperance, and may take place during a debauch--or may arise some time after, during the stage of debility, from a loss of the healthy balance of action between the different parts of the system. This inflammation is sometimes acute, is marked by furious delirium, and terminates fatally in the course of a few days, and sometimes a few hours. At other times it assumes a chronic form, continues much longer, and then frequently results in an effusion of serum, or an extravasation of blood, and the patient dies in a state of insensibility, with all the symptoms of compressed brain. Sometimes the system becomes so saturated with ardent spirit, that there is good reason to believe the effusions, which take place in the cavities of the brain, and elsewhere, are composed, in part at least, of the alcoholic principle. The following case occurred, not long since, in England, and is attested by unquestionable authority.
A man was taken up dead in the streets of London, soon after having drank a quart of gin, on a wager. He was carried to the Westminster Hospital, and there dissected. "In the ventricles of the brain was found a considerable quantity of limpid fluid, distinctly impregnated with gin, both to the sense of smell and taste, and even to the test of inflammability. The liquid appeared to the senses of the examining students, as strong as one-third gin, and two-thirds water."
Dr. Armstrong, who has enjoyed very ample opportunity of investigating this subject, speaks of the chronic inflammation of the brain and its membranes, as frequently proceeding from the free use of strong liquors.