The individuals admitted to this hospital were obtained from the two military camps at the University of Pittsburgh and the Carnegie School of Technology. All of them were enrolled in the army service and ranged from the ages of 18 to 30. They were vigorous individuals, who had passed their physical examinations for the army. The epidemic made its appearance in these camps on October 2, rapidly ascending from a report of two ill on October 2, four on October 3, eight on October 4, to 65 on October 5. On October 11 there were 307 cases in the hospital.

Of these cases 35 died, the day of death being indicated in the following table.

Studies on Epidemic Influenza — Part 153

═══════════════════════════════════════════════╤═══════════════════════ DAY OF DISEASE ON WHICH DEATH OCCURRED │ NUMBER OF CASES ───────────────────────────────────────────────┼─────────────────────── Third │ 1 Fourth │ 3 Fifth │ 4 Sixth │ 4 Seventh │ 4 Eighth │ 5 Ninth │ 3 Tenth │ 4 Eleventh │ 3 Thirteenth │ 1 Fourteenth │ 1 Twentieth │ 1 Twenty-third │ 1 ───────────────────────────────────────────────┴───────────────────────

Studies on Epidemic Influenza — Part 153

The time as indicated in the above table has no relation to the length of time that the patients were ill of pneumonia, but refer to the period of illness from the beginning of the influenza. The duration of the pneumonia is indicated in another table.

Studies on Epidemic Influenza — Part 153

Of the 35 fatal cases 32 came to autopsy. Facilities were available to do the work very satisfactorily, in that the hospital was well provided with a modern post-mortem room and its accessories. The notes on the autopsies were taken immediately and fully, and the materials for subsequent study were collected in different types of preserving fluid. Portions of tissue were collected from all of the organs for microscopical study, while fluids from the chest, lungs, bronchi and heart were obtained for bacteriological investigations and for some chemical analyses.

Added to the above material we also had the opportunity of reviewing and studying the lesions of 18 autopsies performed by Dr. J. W. McMeans. These cases were very similar to our own series, in that they were cases of epidemic influenza amongst soldiers who were being cared for at the St. Francis Hospital. The disease processes were quite alike in the two series, and the analyses made by Dr. McMeans are comparable in our own and serve as a means of checking our results obtained in another institution. The similarity of the lesions in the lungs and other organs serve to indicate that what is reported in this paper is an index of the nature of the lesions of epidemic influenza as it occurred in the Pittsburgh district. In a few instances the autopsies performed by Dr. McMeans revealed more advanced pulmonary lesions with abscess and gangrene than were noted in the cases autopsied at the Military Hospital. The process, however, in the two series of autopsies was identical.