"M. C., admitted into this Hospital, Sept. 30, 1853, in a state of violent raging excitement, depending upon acute mania. She had been in this state three days previous to her admission, and had wandered about the streets in a comparatively naked state, under the excitement of religious enthusiasm. She was a powerful, muscular woman; and to bring her to the Hospital it was necessary to impose upon her the restraint of a strait-jacket. She screamed violently all the way to the Hospital, and used the most threatening language, refusing to listen to anything that was said to her, but when tired of vociferating, contented herself with kicking and spitting at those within her reach. On admission, the mechanical restraint was removed; she was ordered a warm bath, and two grains of the acetate of morphia, and afterwards placed in a bed in a padded room. She continued noisy for an hour or two, and then became quieter; but the attendant, who looked at her every half-hour, always found her sleepless. The following day she continued tranquil, but when addressed, responded with an oath. She was ordered one grain and a half of acetate of morphia. The third day she continued quiet and sullen, but permitted the nurse to dress her and place her in a chair in the day-room with the other patients. The following day (the fourth) she continued tranquil and rational, rather shrinking from conversation; and being a little feverish, was ordered 'henbane,' with a saline. From that day she speedily became convalescent, and was discharged cured, November 11, 1853, having been a patient in the Hospital forty-two days."