While this interesting decision was in the balance, Bernardino was once more in Rome, and able to plead his own cause, for about July 1497 he was recalled there, and spent a year frescoing the castle of Sant' Angelo for the Pope, but in the following year he was back at home, and finished the polyptych for Santa Maria dei Fossi. Probably about this time he married, and he may also have visited Spoleto, besides producing a good many panel paintings, for no very definite work can be assigned to these years in Perugia. He was very naturally engrossed with his new wife, and busy with his little property, and not undertaking any important commissions.
In October of the following year, Cæsar Borgia, son of the painter's great patron, was encamped at Deruta, the little town that lies out among the hills, a few miles west of Perugia. Pintoricchio visited him here while he was resting after his campaign in the Romagna, and obtained an order desiring the vice-treasurer to get permission for him to sink a cistern in his house in Perugia. What interests us even more than this domestic detail is Cæsar's statement that he has "again" taken into his service Bernardino Pintoricchio of Perosa, whom he always loved because of his talents and gifts, and he desires that in all things he shall be treated "as one of ours."[11] Cæsar's expression that he had "again" taken him into his service, suggests that he had not quite recently been retained by the Pope.
Very soon after his visit to the Borgia's camp, he was in treaty with the Cardinal of Spello, thirteen miles from Perugia, to decorate the chapel of his House; but before leaving home he was elected Decemvir of the city, a proof of how high he stood in repute among his fellow-citizens. It could only have been an honorary distinction, for his work in Spello must have taken all his remaining time in Umbria to accomplish. One short visit he was to pay to his own province, but early in 1502 the summons reached him which changed the course of his life. Cardinal Francesco Piccolomini made him the offer which caused him to move to Siena and begin one of his most important undertakings.
Siena is a long journey from Perugia across the hills and plains that lie around Lake Thrasymene, past Chiugi, and so through the breadth of Italy. It brought the painter into new surroundings, and took him quite out of the beaten track. The long and elaborate contract between the Cardinal and the painter must have taken no little time to discuss and agree upon, but it was finished and signed June 29, 1502. During the following autumn and winter, he made his preparations, gathered his workmen and assistants together, and by the spring of 1503 was hard at work in the building, beginning with the ceiling, which we are able, with tolerable certainty, to determine was nearly completed by the autumn.