The 2011 season for the cycling team began in January at the Grand Prix d'Ouverture La Marseillaise and ended in October at Paris–Tours. Cofidis was a UCI Professional Continental team in 2011, meaning they had to be proactively selected by the organizers of UCI World Tour events, including each of the season's Grand Tours, if they were to compete.

The team's most successful rider in 2011 was David Moncoutié. The veteran Frenchman won the Tour Méditerranéen and Tour de l'Ain overall crowns, as well as successes in the Vuelta a España. Moncoutié took a stage win and the King of the Mountains, each for the fourth straight year (a new record for the mountains title). Sprinter Samuel Dumoulin was also a prolific winner, winning six races.

2011 Cofidis season

2011 roster

Ages as of 1 January 2011.

2011 Cofidis season

Riders who joined the team for the 2011 season

Riders who left the team during or after the 2010 season

One-day races

The team was active in races which preceded those known as "classics" and the traditional start of the spring season. At the Grand Prix d'Ouverture la Marseillaise, held in January as the first race of the season in France, El Fares rode to tenth place by finishing in the main field behind the solo winner. In February, Gallopin was the team's best finisher at two of the races in the Vuelta a Mallorca series, coming ninth at the unofficial Trofeo Palma de Mallorca and tenth at the Trofeo Inca.

2011 Cofidis season

Spring classics

Duque took a high placing at the Gran Premio dell'Insubria-Lugano, finishing just off the podium in fourth place, coming home in a group that trailed two leading riders. At Kuurne–Brussels–Kuurne, a race which included most of the sport's top teams, Petit finished ninth in a field sprint finish at the front of the race. Ista narrowly missed out on a victory at Le Samyn in early March. The race's top finishers came across the finish line scattered, in groups of eight or fewer. Ista finished second, alone, 8 seconds back of solo winner Dominic Klemme. Two weeks later, Keukeilere finished fourth in a sprint at Nokere Koerse. Gallopin finished on the podium at Cholet-Pays de Loire. 's Thomas Voeckler won the race with a late attack, with the peloton coming so close to catching him at the finish line that there was no time gap. Gallopin was first from the peloton for second overall. Vogondy rode to fourth place at the Route Adélie de Vitré, just missing the podium after figuring into a winning breakaway.

The team picked up their first single-day win the same day as the more prestigious Tour of Flanders, in which they participated but were not especially competitive, with Duque in 19th their best finisher. The race they won was the inaugural Flèche d'Emeraude, a new race in the UCI Europe Tour and the French Road Cycling Cup. Gallopin came first at the head of a field sprint in Saint-Malo. Zingle figured into a winning breakaway at the Brabantse Pijl, the precursor to the Ardennes classics. He took seventh place, a minute and a half back of the winner Philippe Gilbert. Vogondy was sixth at the Tour du Finistère, finishing with a big main group behind two leaders.

Demaret took the team's second single-day win at the Tartu GP in late May. He was the best of a five-rider breakaway at the front of the race, one which included teammate Taaramäe. That same day, Gallopin took sixth in a sprint finish to the Grand Prix de Plumelec-Morbihan. The team's last race of the early season was Halle–Ingooigem in June, where Sijmens rode to ninth place.

The team was not especially competitive at the spring season's monument classics, coming in 37th at Milan–San Remo, 19th at the Tour of Flanders, 29th at Paris–Roubaix, and 57th at Liège–Bastogne–Liège. The team also sent squads to the Trofeo Laigueglia, Omloop Het Nieuwsblad, Gran Premio di Lugano, Les Boucles du Sud Ardèche, Dwars door Vlaanderen, E3 Prijs Vlaanderen – Harelbeke, Gent–Wevelgem, Scheldeprijs, Paris–Camembert, the Grand Prix de Denain, the Amstel Gold Race, Tro-Bro Léon, La Flèche Wallonne, the Eschborn–Frankfurt City Loop, and the Tallinn-Tartu GP, but finished no higher than 12th in any of these races.