Camacho is a surname of Spanish, Portuguese or French origin. Notable people with the surname include:
Camacho (wrestler), one of the stage names of Tevita Fifita (born 1983), Tongan-American professional wrestler Alejandro Camacho (born 1954), Mexican actor and producer Alicia Sánchez-Camacho (born 1967), Spanish politician Antonio Camacho García (1926–2017), Spanish politician Ariel Camacho (1992–2015), Mexican singer-songwriter Art Camacho, American film director, producer, actor and stuntman Bruno Camacho (born 1985), Brazilian football (soccer) player Byron Camacho (born 1988), Ecuadorian footballer Carlos Camacho (1924–1979), Guamanian politician Carlos S. Camacho (born 1937), Northern Mariana Islands politician Carmen Camacho (born 1939), Filipina singer César Camacho (born 1943), Peruvian-born Brazilian mathematician César Camacho Quiroz (born 1959), Mexican lawyer and politician Christian Camacho (born 1988), American football (soccer) player Daniel Camacho (born 1998), Bolivian football (soccer) player Diego Camacho y Ávila (1652–1712), Spanish archbishop Diego Camacho (footballer) (born 1976), Spanish football (soccer) player Diego Camacho (tennis) (born 1983), Bolivian tennis player Eliodoro Camacho (1831–1899), Bolivian politician Erika Tatiana Camacho (born 1974), Mexican mathematician and academic Ernie Camacho, American baseball player Filemón Camacho (1926–2012), Venezuelan middle-distance runner Frank Camacho (born 1988), Guamanian mixed martial artist Genaro Ruiz Camacho (1954–1998), American drug dealer and organized crime leader Germán Camacho (born 1995), Mexican football (soccer) player Gregorio Camacho (1933–2002), Venezuelan painter Gonzalo Camacho (born 1984), Argentine rugby player Guilherme Camacho (born 1990), Brazilian football (soccer) player Héctor Camacho ("Macho" Camacho) (1962–2012), Puerto Rican boxer Héctor Camacho Jr.