St. George's Chapel is a historic Episcopal chapel located near Angola, Sussex County, Delaware on the Indian River Hundred. It was built in 1794, and is a one-story brick structure measuring 42 feet by 32 feet. It has a brick tower at the southwest corner, built in 1955, and features a restored Palladian window. The original furnishings were removed in 1850 and the roof replaced in 1882 with a steep gable roof. The chapel was restored in 1966. It is joined with All Saints Episcopal Church in the Episcopal Parish of All Saints’ Church & St. George's Chapel.
It was added to the National Register of Historic Places in 1973.