The 2019 San Diego Padres season was the 51st season of the San Diego Padres franchise. The Padres played their home games at Petco Park as members of the Major League Baseball's National League West Division. On September 21, the Padres fired Andy Green as manager. Bench coach Rod Barajas was promoted to interim manager.
The Padres hit a franchise record seven home runs in their 19–4 win against the Toronto Blue Jays on May 25. Though they improved on their record from the previous season, they still failed to qualify for the postseason for the thirteenth straight year.
Season standings
National League West
National League Wildcard
Record vs. opponents
Game log
|-style=background:#bfb;" ||1|| March 28 || Giants || 2–0 || Lauer (1–0) || Bumgarner (0–1) || Yates (1) || 44,655 || 1–0 || W1 |-style=background:#bfb;" ||2|| March 29 || Giants || 4–1 || Lucchesi (1–0) || Holland (0–1) || Yates (2) || 33,769 || 2–0 || W2 |-style=background:#fbb;" ||3|| March 30 || Giants || 2–3 || Rodríguez (1–0) || Margevicius (0–1) || Smith (1) || 41,899 || 2–1 || L1 |-style=background:#bfb;" ||4|| March 31 || Giants || 3–1 || Warren (1–0) || Vincent (0–1) || Yates (3) || 38,444 || 3–1 || W1 |-
|-style=background:#fbb;" ||5|| April 1 || Diamondbacks || 3–10 || Kelly (1–0) || Strahm (0–1) || Duplantier (1) || 18,683 || 3–2 || L1 |-style=background:#fbb;" ||6|| April 2 || Diamondbacks || 5–8 || Greinke (1–1) || Lauer (1–1) || Holland (2) || 22,504 || 3–3 || L2 |-style=background:#bfb;" ||7|| April 3 || Diamondbacks || 4–1 || Lucchesi (2–0) || Ray (0–1) || — || 19,376 || 4–3 || W1 |-style=background:#bbb ||–|| April 4 || @ Cardinals ||Colspan=7|Postponed (rain): Makeup date April 5 |-style=background:#bfb;" ||8|| April 5|| @ Cardinals || 5–3 || Stock (1–0) || Reyes (0–1) || Yates (4) || 46,615 || 5–3 || W2 |-style=background:#bfb;" ||9|| April 6 || @ Cardinals || 6–4 || Wisler (1–0) || Miller (0–1) || Yates (5) || 44,492 || 6–3 || W3 |-style=background:#fbb;" ||10|| April 7|| @ Cardinals || 1–4 || Wainwright (1–0) || Strahm (0–2) || Hicks (1) || 44,340 || 6–4 || L1 |-style=background:#bfb;" ||11|| April 8 || @ Giants || 6–5 || Lauer (2–1) || Moronta (0–2) || Yates (6) || 28,625 || 7–4 || W1 |-style=background:#fbb;" ||12|| April 9 || @ Giants || 2–7 || Holland (1–1) || Lucchesi (2–1) || — || 28,506 || 7–5 || L1 |-style=background:#bfb;" ||13|| April 10 || @ Giants || 3–1 || Margevicius (1–1) || Rodríguez (1–2) || Yates (7) || 28,584 || 8–5 || W1 |-style=background:#bfb;" ||14|| April 11 || @ Diamondbacks || 7–6 || Stammen (1–0) || Bradley (0–1) || Wingenter (1) || 15,449 || 9–5 || W2 |-style=background:#bfb;" ||15|| April 12 || @ Diamondbacks || 2–1 || Reyes (1–0) || Weaver (0–1) || Yates (8) || 22,209 || 10–5 || W3 |-style=background:#bfb;" ||16|| April 13 || @ Diamondbacks || 5–4 || Stammen (2–0) || Andriese (2–1) || Yates (9) || 27,256 || 11–5 || W4 |-style=background:#fbb;" ||17|| April 14 || @ Diamondbacks || 4–8 || Greinke (2–1) || Lauer (2–2) || — || 25,489 || 11–6 || L1 |-style=background:#fbb;" ||18|| April 15 || Rockies || 2–5 || Senzatela (1–0) || Lucchesi (2–2) || Davis (1) || 24,867 || 11–7 || L2 |-style=background:#fbb;" ||19|| April 16 || Rockies || 2–8 || Gray (1–3) || Margevicius (1–2) || — || 24,963 || 11–8 || L3 |-style=background:#fbb;" ||20|| April 18 || Reds || 1–4 || Roark (1–0) || Paddack (0–1) || Iglesias (3) || 26,577 || 11–9 || L4 |-style=background:#fbb;" ||21|| April 19 || Reds || 2–3 || Hughes (2–0) || Stammen (2–1) || Lorenzen (1) || 33,442 || 11–10 || L5 |-style=background:#fbb;" ||22|| April 20 || Reds || 2–4 || Castillo (2–1) || Lauer (2–3) || Iglesias (4) || 37,137 || 11–11 || L6 |-style=background:#bfb;" ||23|| April 21 || Reds || 4–3 || Lucchesi (3–2) || Mahle (0–2) || Yates (10) || 25,932 || 12–11 || W1 |-style=background:#bfb;" ||24|| April 23 || Mariners || 6–3 || Margevicius (2–2) || Swanson (0–2) || Yates (11) || 25,154 || 13–11 || W2 |-style=background:#bfb;" ||25|| April 24 || Mariners || 1–0 || Paddack (1–1) || Hernández (1–2) || Yates (12) || 23,417 || 14–11 || W3 |-style=background:#bfb;" ||26|| April 26 || @ Nationals || 4–3 || Stammen (3–1) || Doolittle (3–1) || Yates (13) || 27,193 || 15–11 || W4 |-style=background:#bfb;" ||27|| April 27 || @ Nationals || 8–3 || Perdomo (1–0) || Suero (1–3) || — || 35,422 || 16–11 || W5 |-style=background:#fbb;" ||28|| April 28 || @ Nationals || 6–7 || Miller (1–0) || Wisler (1–1) || — || 30,186 || 16–12|| L1 |-style=background:#fbb;" ||29|| April 29 || @ Braves || 1–3 || Soroka (2–1) || Margevicius (2–3) || Webb (1) || 19,353 || 16–13 || L2 |-style=background:#bfb;" ||30|| April 30 || @ Braves || 4–3 || Paddack (2–1) || Teherán (2–4) || Yates (14) || 18,626 || 17–13 || W1 |-