The 2019 Challenger Ciudad de Guayaquil was a professional tennis tournament played on clay courts. It was the fifteenth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Guayaquil, Ecuador between October 28 and November 3, 2019.
Singles main-draw entrants
Seeds
1 Rankings are as of 21 October 2019.
Other entrants
The following players received wildcards into the singles main draw: Hugo Dellien Facundo Díaz Acosta Alejandro González Antonio Cayetano March Alexander Zederbauer
The following player received entry into the singles main draw as an alternate: Wilson Leite
The following players received entry from the qualifying draw: Mauricio Echazú Rafael Matos
The following player received entry as a lucky loser: Federico Zeballos
Champions
Singles
Thiago Seyboth Wild def. Hugo Dellien 6–4, 6–0.
Doubles
Ariel Behar / Gonzalo Escobar def. Pedro Sakamoto / Thiago Seyboth Wild 7–6(7–4), 7–6(7–5).