We study the forward self-similar solutions to the $2$D hypodissipative Navier-Stokes equation with fractional diffusion $(-\Delta)^\alpha$ for $\frac{ 1}{ 2}<\alpha<1$. We first show that for arbitrarily large $(1-2\alpha)$-homogeneous initial data which are locally Lipschitz, there exists at least one weak solution whose profile differs from the self-similar profile of the fractional heat equation by an element of $H^\alpha(\mathbb{ R}^2)$. Moreover, when $\alpha\in(\frac{ 2}{ 3},1)$ we show that any such weak solution is actually smooth, hence a strong solution, and satisfies certain far field decay estimates.
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